How to get TRT in 2025: A step-by-step guide to optimizing your testosterone levels

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Should you’ve been feeling a little bit low in multiple side of life, you’re not alone, and chances are high you’re not going loopy, both.

Chances are you'll be experiencing the signs of low testosterone. Testosterone is the intercourse hormone that's accountable for a spread of essential capabilities, from hair progress and bone density to sperm depend and libido ranges.

Low testosterone impacts thousands and thousands of males, and the signs can really feel like a gradual drag on each day life. Almost 39% of males aged 45 years and older have low testosterone, often known as hypogonadism, in keeping with the College of Washington’s Faculty of Public Well being.

The signs should not the identical for everybody, which might make it tougher for males to establish the basis trigger. Some discover their muscle groups trying rather less outlined than they used to. Or, probably, they’ve struggled to take care of power all through the day. Others really feel that they’re intercourse drive is almost non-existent.

Fortuitously, there are therapy choices for males with low testosterone: FDA-approved injections, lotions, gels, tablets, and even pure dietary supplements which might be designed to help testosterone manufacturing.

Discover Out About Our Prime TRT Choose

<img style="aspect-ratio:1;display:block" decoding="async" data-no-modal="true" width="590" height="590" src="https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?w=1024" alt="Ulo Testosterone Replacement Therapy" class="wp-image-36186672" srcset="https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?quality=75&strip=all 1080w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=150,150&quality=75&strip=all 150w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=300,300&quality=75&strip=all 300w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=768,768&quality=75&strip=all 768w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=1024,1024&quality=75&strip=all 1024w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=589,589&quality=75&strip=all 589w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=496,496&quality=75&strip=all 496w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=576,576&quality=75&strip=all 576w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=440,440&quality=75&strip=all 440w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=282,282&quality=75&strip=all 282w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=180,180&quality=75&strip=all 180w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=71,71&quality=75&strip=all 71w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=40,40&quality=75&strip=all 40w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=70,70&quality=75&strip=all 70w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=54,54&quality=75&strip=all 54w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=200,200&quality=75&strip=all 200w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=231,231&quality=75&strip=all 231w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=322,322&quality=75&strip=all 322w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=441,441&quality=75&strip=all 441w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=60,60&quality=75&strip=all 60w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=80,80&quality=75&strip=all 80w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=58,58&quality=75&strip=all 58w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=156,156&quality=75&strip=all 156w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=50,50&quality=75&strip=all 50w, https://nypost.com/wp-content/uploads/sites/2/2025/06/ULO-TRT.jpg?resize=96,96&quality=75&strip=all 96w" sizes="(max-width: 590px) 100vw, 590px"/> Ulo Ulo

Feeling low on power? Ulo gives a customized method to testosterone alternative remedy (TRT), beginning with an at-home lab take a look at and digital session with a licensed supplier. If TRT is advisable, therapy choices — together with injections, gels, and oral drugs — are delivered straight to your door. Plans begin at $159/month. You’ll solely be charged if a supplier determines therapy is acceptable and writes a prescription. Remedy is at the moment obtainable in choose states and contains ongoing help all through your plan. Study extra about the way it works and if it’s obtainable in your state at Ulo’s web site.

“TRT stands for Testosterone Substitute Remedy,” defined Deep Patel, the co-founder of Ulo, a telehealth firm that provides tailor-made TRT protocols. “It’s a means of bringing your testosterone ranges again right into a wholesome vary when your physique isn’t producing sufficient. You’re not taking further. You’re restoring what your system is lacking.”

Should you’re new to the TRT area, chances are high you’re not too conversant in the method for getting a TRT prescription or what varieties of therapies can be found. The excellent news is that Testosterone Substitute Remedy (TRT) has turn into far more accessible by means of professional telehealth clinics like Ulo.

The Submit has consulted a number of males’s well being specialists and leaders within the hormone area to create a step-by-step information to getting TRT in 2025.

1. Contemplate your signs

Low testosterone can manifest by means of numerous signs. These embrace low intercourse drive, hassle focusing, temper swings or irritability, lack of muscle or energy regardless of understanding, fixed fatigue (even whenever you’re sleeping sufficient), elevated stomach fats, and even melancholy or nervousness.

In keeping with Patel, many guys affected by ‘Low T’ really feel like they’re hitting a wall relating to their bodily well being and total well-being. “The commonest issues guys say are ‘I can’t focus like I used to,’ ‘I really feel flat mentally, bodily, sexually,’ ‘I’ve misplaced my drive,’ ‘I work out and eat clear however don’t see outcomes,’ ‘I simply don’t really feel like me anymore,'” he shared.

Typically they’ve tried all the pieces else — higher sleep, totally different diets, dietary supplements, way of life modifications. “TRT is never the very first thing they fight,” stated Patel. “However for a lot of with genuinely low ranges, it’s the answer that lastly works.”

2. Seek the advice of a males’s well being skilled or discover a professional on-line TRT clinic

After figuring out signs, the subsequent step is to contemplate totally different suppliers. There are just a few totally different choices for males all for studying extra about TRT.

For anybody searching for medical recommendation, it’s essential to seek the advice of your major care doctor, particularly earlier than beginning a brand new healthcare or wellness routine. Main care physicians are additionally capable of entry your medical historical past, which is essential to contemplate when beginning TRT.

These days, there are extra on-line clinics providing TRT providers. The problem is discovering one that's professional, inexpensive, and gives providers which might be tailor-made to your particular wants. Websites like Hone, Ulo, Hims, and PeterMD supply well-regarded testosterone providers, with totally different therapy plans obtainable.

“There are many clinics that publicize TRT on-line,” prompt Dr. Michael Aziz, an anti-aging internist and regenerative medication specialist at Lenox Hill Hospital in New York Metropolis. “However, sufferers ought to solely contemplate clinics which have physicians who're board-certified and are specialised in endocrinology, urology, and inside medication with anti-aging coaching.”

Aziz added that sufferers also needs to learn the web critiques concerning the docs’ expertise, and search for optimistic suggestions about ease of communication, in addition to speedy response to points and coverings.

It’s additionally essential to confirm that the clinic is utilizing professional U.S.-based pharmacies and is absolutely compliant with telehealth legal guidelines and DEA laws for managed substances.

3. Get your bloodwork completed

To get a testosterone prescription, you’ll must take a TRT blood take a look at. TRT blood assessments study the quantity of the male hormone current within the blood.

Some assessments supply extra detailed analyses than others, together with extra well being markers, reminiscent of free and complete testosterone, intercourse hormone-binding globulin (SHBG), the prostate-specific antigen (PSA), and different hormones that may very well be affected by TRT. These assessments are most correct when administered within the morning, when testosterone ranges peak.

The conventional testosterone vary is taken into account to be wherever between 300 and 1,000 nanograms per deciliter. The FDA solely approves TRT for particular circumstances, reminiscent of hypogonadism or diminished practical exercise of the gonads. Most clinics additionally solely contemplate testosterone prescription for males who're experiencing signs and have ranges underneath 300 ng/dl.

In the present day, TRT clinics can mail blood assessments to your door. At-home assessments require a easy finger prick that you are able to do your self and ship again to a laboratory for evaluation.

4. Await a prognosis and prescription

After a licensed well being supplier evaluates your blood work, it’s essential to satisfy with them to debate your signs and medical historical past.

“The clinic ought to require complete labs, an in depth consumption course of, and an actual dialog with a educated supplier,” stated Tomo Marjanovic, the proprietor of Aspire Rejuvenation Clinic, a wellness middle specializing in personalised hormone remedy.

Marjanovic warned that if the one interplay is an automatic signup type or a rushed seek the advice of, that could be a pink flag. Analysis ought to by no means depend on numbers alone — some males at his clinic expertise critical signs, even when their testosterone ranges are barely over 300ng/dl.

Along with scientific signs and hormone ranges, Marjanovic considers a affected person’s household historical past (particularly coronary heart illness, prostate points, and hormone issues) and way of life elements (reminiscent of stress, eating regimen, sleep, and substance use).

“If scientific signs align with hormone deficiencies confirmed by lab outcomes, the supplier might prescribe TRT. This isn’t one thing it's best to get from a easy on-line type as a result of it’s a medical remedy that wants actual analysis, not checkbox medication,” he defined.

5. Contemplate the fee and verify along with your insurance coverage for protection choices

Make sure to verify along with your insurance coverage supplier to see if TRT is roofed. Most suppliers require sufferers to satisfy sure thresholds and supply medical documentation that signifies their testosterone has fallen under the conventional ranges, along with recorded signs.

The price of TRT will depend upon the kind of therapy you have an interest in. Most testosterone injections price between $50 and $150, oral tablets round $300, and patches can attain $400.

There are particular telehealth corporations that supply broader well being providers, which can embrace TRT. Subscription plans can vary from $100 to $300 per 30 days.

6. Contemplate the potential advantages and dangers

TRT comes with an a variety of benefits; all the pieces from elevated power on the gymnasium to raised sleep at night time, enhanced temper, and improved intimate efficiency.

“When completed proper, TRT can provide you your life again,” Patel identified. “The advantages individuals report most frequently are far more power, higher exercises and sooner restoration, greater libido, clearer considering and focus, emotional stability, and a way of drive and confidence that returns.”

A 2019 examine on prescription testosterone discovered that 52% of males claimed testosterone improved their power, 42% noticed enhancements of their libido, and 29% reported muscle progress. Whereas there are a number of advantages, Patel and plenty of different specialists are very clear concerning the potential dangers related to TRT.

“The commonest negative effects embrace zits, water retention, or elevated pink blood cell counts, which might thicken your blood. Some males expertise testicular shrinkage or lowered fertility. There are additionally issues about cardiovascular dangers in sure populations, significantly males with present coronary heart circumstances,” he defined.

It’s essential to contemplate that TRT considerably suppresses pure testosterone manufacturing, which might additionally scale back sperm manufacturing. If fertility is essential to you, Patel mentions there are drugs like HCG or clomiphene that may be taken alongside TRT to protect it.

In a 2021 examine, over 90% of males maintained regular sperm counts when utilizing these fertility-preserving drugs with TRT.

7. Talk about therapy plans

There are just a few totally different types of TRT obtainable, and most respected on-line TRT clinics supply several types of TRT to cowl people’ wants and preferences.

“The clinic’s method to TRT must be complete slightly than simply giving a script for testosterone therapy,” Aziz burdened. “The supply technique of TRT is greatest chosen by each the physician and the affected person primarily based on the affected person’s way of life and signs.”

Aziz says that totally different gels, lotions, tablets, and injections are well-researched and vetted. Nevertheless, some variations have to be noticed: “Gels are used each day however might be transferred to sexual companions and kids. Injections might be self-injected as soon as to twice every week, or administered by the physician each 10 weeks.”

Most specialists agree that injections constantly supply probably the most predictable outcomes. An article in The Journal For Nurse Practitioners outlines probably the most viable therapy choices, citing that Depo-Testosterone is probably the most cost-efficient TRT possibility and Androderm is probably the most efficacious TRT remedy, with as much as 92% of sufferers reaching regular testosterone ranges with constant use.

8. Begin therapy and look forward to the outcomes

Many on-line TRT clinics can ship therapy to your entrance door as quickly because the prescription is in place. However that’s only the start of the method; it takes a while to really feel and see the advantages, and the timeline can even depend upon the type of therapy you’re utilizing.

“As for outcomes, most guys really feel a distinction inside 4 to 6 weeks. Extra power, higher temper, stronger libido,’ Patel defined.

He stated that physique composition modifications — like extra muscle and fewer fats — normally take a bit longer to note. Some bodily modifications might be anticipated round two to a few months.

“I keep in mind one individual telling us he knew it was working when he awakened one morning and really needed to go to the gymnasium for the primary time in years,” Patel exclaimed.

It’s not simply modifications in efficiency or look, however how males view themselves. “Extra power, stronger intercourse drive, higher exercises, and a way of confidence they hadn’t felt in years,” he added.

9. Monitor progress and regulate protocols if needed

As soon as you start your therapy, it’s crucial to observe your outcomes, look ahead to any potential negative effects, and talk brazenly along with your suppliers.

“TRT isn’t a one-and-done remedy as a result of hormones are dynamic, and therapy ought to evolve primarily based on common lab monitoring and affected person suggestions,” Marjanovic defined. With out correct prognosis and ongoing monitoring, you danger underdosing, overdosing (lots of people don’t assume this could occur, however it will probably), or ignoring different hormonal imbalances like estrogen dominance or thyroid dysfunction that may derail progress.”

Marjanovic recommends that TRT suppliers repeat labs each 8 to 12 weeks early in remedy, verify signs recurrently, and make any changes needed. It’s essential to handle any markers that might signify negative effects, together with elevated hematocrit, estrogen imbalances, or libido points.

“Personalised plan means tailoring dosage, supply technique, ancillary meds (like enclomiphene and hCG if wanted), and way of life help primarily based on particular person wants. That is all essential…” he defined. “TRT with out follow-up isn’t remedy — it’s playing.”

This text was written by Miska Salemann, New York Submit Commerce Author/Reporter. As a health-forward member of Gen Z, Miska seeks out specialists to weigh in on the advantages, security and designs of each trending and tried-and-true health gear, exercise clothes, dietary dietary supplements and extra. Taking issues into her personal fingers, Miska intrepidly assessments wellness merchandise, starting from Bryan Johnson’s Blueprint Longevity Combine to residence gymnasium elliptical machines to Jennifer Aniston’s favourite exercise platform – usually along with her lovely one-year previous daughter by her aspect. Earlier than becoming a member of The Submit, Miska coated way of life and client subjects for the U.S. Solar and The Cannon Seashore Gazette.